YAF2 anticorps (Middle Region)

N° du produit ABIN1109525

L’anticorps Lapin Polyclonal anti-YAF2 a été validé pour WB et IHC (p). Il convient pour détecter YAF2 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet et Xenopus laevis.

Aperçu rapide pour YAF2 anticorps (Middle Region) (ABIN1109525)

Antigène: YAF2 (YY1 Associated Factor 2 (YAF2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YAF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-YAF2 anticorps

Épitope: Middle Region

Séquence: KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK

Réactivité croisée (Details): Species reactivity (expected):Dog, Rat, Mouse, Bovine, Chicken, African clawed frogSpecies reactivity (tested):Human

Purification: Purified on Protein A affinity column

Immunogène: The immunogen for anti-YAF2 antibody: synthetic peptide directed towards the middle region of human YAF2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Date de péremption: 12 months

Détails sur YAF2

Antigène: YAF2 (YY1 Associated Factor 2 (YAF2))

Autre désignation: YAF2

Sujet: YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.Synonyms: YY1-associated factor 2

ID gène: 10138

NCBI Accession: NP_005739